Isidore de Seville offers learner activity programs in support of its academic curriculum. These programs aim to enhance learner's talents and leadership skills based on their interests and preferences. Teacher who are experts in the field are assigned as club moderators. A learner is entitled to join at least one club every semester.
The Supreme Pupil Government is composed of elected officers from Grades 4 to 6 who embody the spirit of leadership and camaraderie. As the official representatives of the learner body, members of the SPG are expected to demonstrate the qualities of a good leader and to carry out their roles and responsibilities with integrity and excellence.